Physical issues that can cause low libido include low testosterone, prescription medicines, too little or too much exercise, and alcohol and drug use. Psychological issues can include depression, stress, and problems in your relationshipLibido is a person's overall sexual drive or desire for sexual activity. Libido is influenced by biological, psychological, and social factors. Biologically, the sex hormones and associated neurotransmitters that act upon the nucleus accumbens regulate libido in humans.

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